Big Pharma might be shaking in its boots after a new survey revealed that nearly half of CBD users have stopped using traditional medicines and substituted them with medical marijuana.

The new statistics come from a joint study by HelloMD (a cannabis doctor/patient resource site) and the Brightfield Group (a cannabis data firm). According to their survey of 2,400 CBD users, 42 percent have stopped using both over the counter drugs like ibuprofen and prescription medications such as Vicodin in favor of cannabidiol treatment, as reported by Forbes.

80 percent of respondents said that in their experience CBD extract was “very or extremely effective,” while only 3 percent found it be slightly effective or not at all effective. Ailments most commonly treated by CBD were joint pain, anxiety, depression, and insomnia, according to the survey.

The survey also found some other interesting trends in CBD use. For instance, gender seemed to play a role in users’ favorite cannabinoids. While 55 percent of CBD users were female, men preferred THC-dominant cannabis products.

“We are seeing an exponential rise in the interest of CBD products from our patient community—particularly among women,” said Dr. Perry Solomon, chief medical officer at HelloMD, as reported by Green Rush Daily. “While we still have much to learn about CBD, we cannot ignore this one fact; the majority of those using CBD products today receive great benefit. This has the potential for far-reaching consequences.”

Also revealed in the survey was that some users are confused about just what is in the CBD products they use. While you can get CBD-rich concentrates more easily in states with medical marijuana programs, users in states without a legal framework sometimes buy their stuff from online vendors. Very often, what’s sold as CBD oil online is manufactured from hemp, which makes it legal but not very high in cannabinoids. Hemp is not particularly rich in CBD, and to extract that cannabinoid from hemp requires “harsh chemicals,” according to reporting from Leafly.

Still, CBD shows promise as a safe alternative to some addictive, side-effect inducing pharmaceuticals. “This study is exciting because it shows there is potentially a huge barely-tapped market for CBD products that could improve the lives of many people,” Bethany Gomez, Director of Research at Brightfield Group, told High Times.

“With further research and public education, CBD could be an effective alternative treatment for many people.”

Photo via Flickr user Me